Recent questions in Biochemistry

by admin (2.6k points) in Biochemistry asked Sep 15

A 45-year-old white woman presents to her physician complaining of several months of worsening shortness of breath. Previously she was told she had asthma because she was hav- ing intermittent episodes of wheezing com- bined with a productive cough and difficulty catching her breath. She used to run two miles every morning but can no longer walk more than 10 city blocks without stopping. She has never smoked. On physical examination she is using her accessory muscles to assist with res- piration. Pulmonary examination is notable for an increased decreased FEV1/FVC ratio, decreased air movement with each breath, and increased resonance upon percussion. X-ray of the chest is shown in the image. Which of the following is the most likely underlying cause for this patient’s disease?

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by admin (2.6k points) in Biochemistry asked Sep 15

A nucleic acid fragment is added to four dif- ferent tubes along with a polymerase, a radio- labeled primer, and deoxynucleotides. Each tube also contains one of the four bases as dideoxynucleotides. The four tubes are then run on electrophoresis gel and visualized by autoradiography. For which of the following purposes would the described laboratory tech- nique be utilized?

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by admin (2.6k points) in Biochemistry asked Sep 15

A 57-year-old woman visits her primary care physician. Laboratory studies reveal an LDL of 194 mg/dL and HDL of 41 mg/dL. Her phy- sician begins therapy with a drug that inhibits production of mevalonic acid. Which of the following is a common side effect of this ther- apy?

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by admin (2.6k points) in Biochemistry asked Sep 13

A patient who is a carrier of sickle cell trait presents to the clinic. The single base-pair mu- tation for sickle cell anemia destroys the MstII restriction enzyme recognition site represented by an asterisk in the image. The restriction enzyme-binding sites are shown as arrows on the map. DNA from this patient is treated with MstII and run on an electrophoresis gel. The DNA is then hybridized with a labeled probe that binds to the normal gene in the posi- tion shown on the map. In the Southern blot shown in the image, which lane represents the patient?

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by admin (2.6k points) in Biochemistry asked Sep 13

A metabolic process is pictured below. Which intermediate in this process inhibits the rate- limiting enzyme of glycolysis and activates the rate-limiting enzyme of fatty acid synthesis?

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by admin (2.6k points) in Biochemistry asked Sep 10

A 6-year-old boy presents to his pediatrician with skin lesions all over his body. For several years he has been very sensitive to sunlight. Neither the boy’s parents nor his siblings have the same skin lesions or sun sensitivity. Biop- sies of several of the boy’s lesions reveal squa- mous cell carcinoma. Which mutation would one expect to see in this patient’s DNA?

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Recent questions in Biochemistry

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