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A 32-year-old woman presents to her physician for the third time in six months. She has been feeling very tired and depressed, and has come to talk about starting antidepressants. She also complains of a 4.5-kg (10-lb) weight gain over the past three months. During her physical examination the physician notices that she is wearing a sweater and a coat, despite the room being at a warm temperature. Problems with the thyroid are suspected, and a biopsy is per- formed (see image). This woman may have a human leukocyte antigen subtype that also in- creases her risk of which disease?

(A) Multiple sclerosis
(B) Pernicious anemia
(C) Psoriasis
(D) Steroid-responsive nephrotic syndrome

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