Question

A 15-year-old boy presents with prolonged fa- tigue and mild jaundice following a serious infection. Blood tests reveal hemoglobin of 10.5 g/dL and an elevated reticulocyte count. A peripheral blood smear reveals Heinz bodies. Which of the following best describes the nor- mal action associated with this patient’s meta- bolic defect?

1. (A)  To generate glucose-6-phosphate in all cells

2. (B)  To generate glucose-6-phosphate in RBCs only

3. (C)  To generate mucopolysaccharides

4. (D)  To regenerate reduced nicotinamide ade nine dinucleotide phosphate in all cells

5. (E)  To regenerate reduced nicotinamide adenine dinucleotide phosphate in RBCs only