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A 52-year-old man with a 12-year history of poorly controlled diabetes mellitus presents to his physician complaining of changes in his vi- sion. Physical examination reveals opacities on the lens of the eye similar to those seen in this image. Which enzyme most likely contributed to this complication?

(A) 3-Hydroxy-3-methylglutaryl coenzyme A reductase

(B) Adenosine deaminase
(C) Aldose reductase
(D) Galactose-1-phosphate uridyltransferase (E) Hexokinase
(F) Insulin-like growth factor

 

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